Editorial Commentary: When Treating Cartilage Lesions With Osseous Involvement, Biologic “Chondrofacilitation” Using Either Bone Marrow Aspirate Concentrate or Mesenchymal Stem Cells Augments Microfracture

The use of biologic augmentation following microfracture for symptomatic cartilage defects the knee with osseous involvement shows encouraging results. Bone marrow aspirate concentrate provides growth factors to injury site, such as vascular endothelial factor, platelet-derived transforming factor-βa, and bone morphogenetic proteins in addition mesenchymal stem cells present concentrate. Cellular-based therapies like are becoming more widely used conjunction surgical treatment focal lesions early promising Both options improve clinical radiographic outcomes. As efficacy versus concentrate, we believe that both have